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KMID : 0356919930260061284
Korean Journal of Anesthesiology
1993 Volume.26 No. 6 p.1284 ~ p.1288
A Case of Withdrawal symptomafter Injection of Nalbuphine in a Chronically Morphine-Dependent Patient
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Abstract
Nalbuphine, a mixed agonist-antagonist type opioid, can precipitate abstinence syndrome in opioid-dependent patients especially in large doses. We can prevent this syndrome by avoiding the injection of agonist-antagonist type opioid to the
patient
who
already has used opioid for a long time, and the method of relatively small dose increments in its use. We experienced a case of opioid withdrawal symptom in chronically morphine-administered patient via epidural catheter after using
intramuscular
nalbuphine for analgesia. The symptom was promptly relieved by intravascular morphine injection without any problems.
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